| On a perfect planet anyone who
suspected that they were autistic, epileptic or |
| otherwise genetically challenged
ought to get a full genome analysis.
That way, as far as |
|
current knowledge is aware, one knows all or probably most of
one's genetic liabilities. |
|
That means there has to be a database by gene and specific
mutation that resolves
|
|
to a syndrome. As mentioned previously, it is certainly the case
that one might show
|
|
symptoms of something without a known genetic defect or that one
might not show
|
| symptoms despite a known genetic
effect. These are both, at one's discretion, interesting |
| research areas.
If the results come back, for example, that someone has |
|
1. Down Syndrome translocation 14 p15 (= extra parts of
chromosome 21 attach to
|
|
chromosome 14 in the p15 region. Down Syndrome translocations
have been found |
|
involving chromosomes 13, 15 and 22. It is an active area of
research to describe what |
| parts or copies of chromosome 21 went
where. As far as I am aware, no one has |
| reported multiple translocations in
the same person. |
| 2. a mutation in the HLA-DOB1 gene
associated with an intolerance to gluten |
| 3. a mutation in the AP3B2 gene
associaed with epileptic encephalopathy type 48 |
| 4. a mutation in the RAI1 gene
associated with circadian rhythm disruption |
| then schools, insurance companies,
Social Security, law enforcement and judicial |
| systems at the Federal, state, county
and municipal levels can operate from a common |
| basis. In the early 18th century
communications were slow, translation from one |
| language to another was tedious,
medicine was primitive, diseases were rampant, war |
| was frequent and Johan Gregor Mendel,
a friar of the Order of Saint Augustine, had |
| yet to found the science of genetics.
Today we have none of those excuses. We all need |
| one database that defines human
genetic variations. If a government or agency does not |
|
wish to use the data to help the people it bears
responsibility for it has be pointed out |
|
that governments and societies go extinct just like species
do. The United States of |
| America should, for a variety of
reasons, lead the effort. If the United States cannot, |
| then California, for the same
reasons, should take up the responsibility of leadership. |